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Medchemexpress LLC Lm10 | 1316695-35-8 | 99.9% | 229.22 | 50 MG
Supplier: Medchemexpress LLC HY3329850MG
LM10 is a potent inhibitor of tryptophan 2,3-dioxygenase (TDO), an hepatic enzyme that degrades tryptophan along the kynurenine pathway. This compound shows potential for research in cancer diseases. It exhibits good TDO inhibition (Ki = 5.6 μM) with a competitive inhibition profile and does not inhibit IDO. LM10 has high solubility and bioavailability without obvious signs of toxicity.
- Potent inhibitor of tryptophan 2,3-dioxygenase (TDO).
- Potential for cancer disease research.
- Displays good TDO inhibition (Ki = 5.6 μM) with a competitive inhibition profile.
- Does not inhibit IDO.
- High solubility and bioavailability.
- No obvious signs of toxicity.
- Prevents the growth of TDO-expressing P815 tumor cells in vivo.
- Promotes better rejection of control clone P815B cl1, which does not express TDO, in vivo.
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