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Medchemexpress LLC LMP2A (426-434) | 152274-91-4 | 96.1% | 906.16 | 25 MG
Supplier: Medchemexpress LLC 25MGHYP5470
LMP2A (426-434) is an HLA-A2-restricted cytotoxic T lymphocyte (CTL) epitope of Epstein-Barr virus (EBV) latent membrane protein 2A (LMP2A). It can trigger an immune response in individuals expressing various HLA-A*02 subtypes and induces a strong IFN-γ secretion response, leading to a high proportion of CD8+ IFN-γ+ T cells. It induces specific CTLs that effectively kill target cells expressing LMP2A.
- Suitable for studying EBV-related malignant tumors, such as Hodgkin's disease and nasopharyngeal carcinoma.
- Induces IFN-γ secreting cells at a frequency of 80.6 SFC/5x10⁴ CD8+ T cells (at 20 μg/mL for 24 h).
- Significantly increases the proportion of CD8+IFN-γ+ cells after two weeks of stimulation (at 20 μg/mL).
- Specific CTLs effectively kill peptide-pulsed T2 cells and 293T-LMP2A cells (at 20 μg/mL for 4 h).
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