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Cayman Chemical LNP Encapsulation Buffer Tabl
SDP

Supplier:  Cayman Chemical 4008121 EA

Encompass_Preferred

A multi-kinase inhibitor inhibits CK2 (IC50 0.098 UM) the PI3K subunits p110a p110B p110 and p110Y (IC50s 0.497 0.554 0.331 and 3.8 UM respectively) and DNA-PK (IC50 6 UM) among other kinases as well as CK1 GSK3a and GSK3B by greater than 40 at 10 UM reduces viability of SGC-7901 cells at 12.5 25 and 50 UM induces apoptosis and autophagy in SGC-7901 cells at 50 UM reduces tumor volume in DLD-1 and LoVo mouse xenograft models at 2 ng/ml/kg reduces aging-induced increases in the number of aging SA-b-gal-positive human VSMCs at 20 UM in the 5th to 15th generations

Catalog No. 50-294-2347


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