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Medchemexpress LLC Lobeline hydrochloride | 134-63-4 | 99.9% | 5 MG
Supplier: Medchemexpress LLC HYB09795MG
Lobeline (α-Lobeline) hydrochloride is a brain-penetrant nicotinic receptor agonist. It increases dopamine (DA) release by inhibiting DA uptake into synaptic vesicles and altering presynaptic DA storage. Lobeline hydrochloride is effective in smoking cessation.
- Evokes [3H]DA overflow calcium-independently
- Inhibits [3H]DA uptake into synaptosomes and vesicles
- Decreases d-methamphetamine self-administration in rats
- Increases tolerance development to d-methamphetamine
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