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Selleck Chemical LLC Lodoxamide E4875-1G
Supplier: Selleck Chemical LLC E48751G
Lodoxamide (U-42585E free acid) is a potent agonist of GPR35 with an EC50 of 1 nM It also inhibits eosinophil peroxidase release after IgA activation and reduces eosinophil cationic protein and eosinophil-derived neurotoxin suggesting direct effects on eosinophils It is a mast cell stabilizer used to treat asthma allergic conjunctivitis and superior limbic keratoconjunctivitis
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