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Cayman Chemical LomerIzInhydrochlorIde 100mg
Supplier: Cayman Chemical 28374100 MG
A voltage-dependent calcium channel blocker; inhibits low- and high-voltage activated calcium currents in rat hippocampal CA1 pyramidal neurons (IC50s = 1.9 and 4 μM, respectively); inhibits vasoconstriction induced by potassium chloride, 5-HT, or vasopressin in isolated rat basilar arteries at 1 μM; reduces neurotoxicity induced by glutamate, NMDA, or kainate in rat retinal primary cell cultures at 1 μM; reduces retinal damage in a rat model of retinal ischemia-reperfusion injury at 1 mg/kg
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