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Medchemexpress LLC Lometrexol disodium | 120408-07-3 | 98.0% | C21H23N5Na2O6 | 1 MG
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Supplier:  Medchemexpress LLC HY14521A1MG

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Lometrexol disodium is an antipurine antifolate that inhibits glycinamide ribonucleotide formyltransferase (GARFT) and human Serine hydroxymethyltransferase1/2 (hSHMT1/2). This leads to the inhibition of de novo purine synthesis, causing abnormal cell proliferation, apoptosis, and cell cycle arrest, thus exhibiting anticancer activity.

  • Inhibits purine synthesis.
  • Induces cell apoptosis.
  • Causes cell cycle arrest.
  • Demonstrates anticancer properties.

Catalog No. 50-003-55757


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