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Medchemexpress LLC Lometrexol hydrate | 1435784-14-7 | 99.0% | C21H27N5O7 | 10MG
Supplier: Medchemexpress LLC HY14521B10MG
Lometrexol hydrate is an antipurine antifolate research compound that inhibits glycinamide ribonucleotide formyltransferase (GARFT) and disrupts de novo purine synthesis, resulting in cell cycle arrest and apoptosis. It is used in biochemical and cellular studies to probe purine metabolism, antifolate mechanisms, and related cancer biology pathways.
- Inhibits GARFT and impairs purine biosynthesis.
- Reported activity against human serine hydroxymethyltransferase 1/2 (hSHMT1/2).
- High reported purity suitable for research applications.
- Available as a solid hydrate for convenient storage and handling.
- Soluble in DMSO for preparation of concentrated stock solutions.
- Provided in small pack sizes suitable for assay development and screening.
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