Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Apexbio Technology LLC Lonafarnib 193275-84-2 200mg
Supplier: Apexbio Technology LLC A4379200
Lonafarnib (CAS 193275-84-2) also known as SCH66336 or Sarasar is a tricyclic orally bioavailable inhibitor of farnesyltransferase (FTase) functioning without peptide or sulfhydryl groups FTase mediates post-translational farnesylation of Ras proteins a modification required for their membrane localization and activation of downstream signaling pathways involved in cellular growth proliferation and survival By inhibiting this enzymatic activity Lonafarnib disrupts Ras translocation to the plasma membrane limiting Ras-mediated signaling Currently Lonafarnib is widely evaluated in preclinical and clinical investigations particularly in oncology contexts
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?