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Apexbio Technology LLC Lornoxicam 70374-39-9 200mg
Supplier: Apexbio Technology LLC B1441200
Lornoxicam (CAS 70374-39-9) is an oxicam-class nonsteroidal anti-inflammatory drug (NSAID) that exerts its pharmacological effects primarily by potent inhibition of cyclooxygenase isoforms COX-1 and COX-2 with in vitro IC50 values of 5 nM and 8 nM respectively Studies in intact human cells and whole blood confirm its strong suppressive activity against both COX isoenzymes Additionally lornoxicam displays dose-dependent inhibition of nitric oxide formation (IC50 65 M) and reduction of IL-6 production in vitro Due to its robust COX inhibition and favorable pharmacokinetic profile lornoxicam is widely utilized as a research tool in studies investigating inflammation pain pathways and COX-mediated prostaglandin synthesis
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