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Medchemexpress LLC Losartan-d4 (carboxylic acid) | 1246820-62-1 | 98.1% | 1 MG

Supplier: Medchemexpress LLC HY12765S1MG
Losartan-d4 carboxylic acid (E-3174-d4) is a deuterium-labeled Losartan Carboxylic Acid. It is an active carboxylic acid metabolite of Losartan and an angiotensin II receptor type 1 (AT1) antagonist. It blocks angiotensin II-induced responses in vascular smooth muscle cells (VSMC) and elevates plasma renin activities while reducing mean arterial pressure.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
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