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Cayman Chemical Losartn CarboxylIc AcId 50mg
Supplier: Cayman Chemical 1595750 MG
An AT1b receptor antagonist and active metabolite of losartan; an antagonist of AT1b (Kis = 0.67 nM in COS-7 cells expressing the human receptor); selective for AT1b over AT2 (Ki = >10,000 nM in COS-7 cells expressing the human receptor); reduces U-44619-induced aggregation of platelets in isolated human platelet-rich plasma at 50 µM; reduces MAP in water-deprived rats at 1 mg/kg
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