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Cayman Chemical LoureIrIn B 10mg
Supplier: Cayman Chemical 2745410 MG
A flavonoid with diverse biological activities; inhibits Kv1.3-mediated currents, induces membrane depolarization, and reduces calcium influx in Jurkat T cells; inhibits phytohemagglutinin-induced IL-2 release in Jurkat T cells; reduces type I collagen and fibronectin protein levels in TGF-β1-stimulated fibroblasts as well as contraction of TGF-β1-stimulated fibroblasts in a gel contraction assay at 25 μg/ml; reduces type I collagen and fibronectin protein levels and inhibits phosphorylation of ERK and JNK in isolated human hypertrophic scar tissue; increases glucose absorption and intracellular ATP levels in Ins-1 cells
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