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Medchemexpress LLC Lovastatin | 75330-75-5 | 404.54 | 250 MG
Supplier: Medchemexpress LLC 250MGHYN0504
Lovastatin is a cell-permeable HMG-CoA reductase inhibitor used to lower cholesterol. In its active form, it inhibits the enzyme HMG-CoA reductase, significantly reducing apolipoprotein-B-containing lipoproteins like LDL cholesterol and plasma triglycerides, while slightly increasing HDL cholesterol. It also effectively reduces cell viability and induces apoptosis in HepG2 cells.
- Inhibits HMG-CoA reductase
- Reduces HepG2 cell viability at 10 μM
- Induces HepG2 cell apoptosis at 10 μM
- Purity: 99.75%
- Appearance: Solid
- Color: Off-white to light yellow
- Molecular weight: 404.54
- Formula: C24H36O5
- Targets: HMG-CoA reductase (HMGCR), autophagy, ferroptosis
- Pathways: Metabolic enzyme/protease, autophagy, apoptosis
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