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Cayman Chemical LoxapInsuccInate 50mg

Supplier: Cayman Chemical 2076050 MG

A secoiridoid polyphenol with diverse biological activities inhibits the proliferation of CWR-R1ca PC3 PC-3M and DU145 cells (IC50s 3 59 0 64 1 03 and 5 35 UM respectively) inhibits the growth of L major promastigotes and amastigotes in vitro (IC50s 18 7 and 87 Ug/ml respectively) and reduces lymph node parasite burden in a mouse model of leishmaniasis at 5 mg/kg reduces hippocampal AB levels in a TgSwDI transgenic mouse model of Alzheimers disease at 5 mg/kg decreases serum IL-6 and TNF-a levels and reduces lung cell apoptosis in a chicken model of LPS-induced acute lung injury at 5 mg/kg
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