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Medchemexpress LLC LQZ-7I | 195822-23-2 | 99.8% | 348.35 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY13653810MM/1ML

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LQZ-7I is a survivin-targeting inhibitor that inhibits survivin dimerization. It effectively inhibits xenograft tumor growth orally and induces survivin loss in tumors. This compound is for research use only.

  • Inhibits survivin dimerization.
  • Suppresses tumor growth in male NSG mice without notable adverse effects.
  • Exhibits improved cytotoxicity with IC50s of 3.1 μM against C4-2 cells and 4.8 μM against PC-3 cells.
  • Selectively reduces survivin expression without affecting XIAP, cIAP1, and cIAP2.

Catalog No. 50-003-48316


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