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Medchemexpress LLC LR-90 | 245075-84-7 | 99.2% | C₃₅H₃₄Cl₂N₄O₈ | 1 ML
Supplier: Medchemexpress LLC HY7638310MM/1ML
LR-90 is an advanced glycation end product (AGE) inhibitor that has shown to inhibit inflammatory responses in human monocytes. It is also utilized in research concerning diabetic animal models.
- Inhibits AGE formation.
- Reduces inflammatory responses in human monocytes.
- Applicable in research related to diabetic animal models.
- Inhibits RAGE, MCP-1, COX-2, IP-10, and NOX2 mRNA expression in THP-1 cells.
- Blocks THP-1 cell adherence to endothelial cells.
- Has no significant effect on the viability of THP-1 cells at tested concentrations.
- Significantly reduces plasma lipids and modestly affects hyperglycemia in ZDF rats.
- Decreases renal AGE, AGER, and lipid peroxidation.
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