Thermo Scientific™ LRRK2 [G2019S] Recombinant Protein

Catalog No.	Quantity
A15201	100 μg

Catalog No. A15201 Supplier Thermo Scientific™ Supplier No. A15201

Description

Recombinant Protein

LRRK2 (Leucine Rich Repeat Kinase 2) is a Protein Coding gene. Diseases associated with LRRK2 include Parkinson Disease 8, Autosomal Dominant and Hereditary Late-Onset Parkinson Disease. Among its related pathways are Signaling by PTK6 and ncRNAs involved in Wnt signaling in hepatocellular carcinoma. Gene Ontology (GO) annotations related to LRRK2 (G2019S Mutant) include protein homodimerization activity and transferase activity, transferring phosphorus-containing groups. An important paralog of LRRK2 (G2019S Mutant) is TNNI3K. Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene, which codes for a multidomain protein kinase, are considered the most common genetic cause of late-onset autosomal-dominant Parkinson's disease.

Specifications

• Accession Number: Q5S007
• Concentration: See Label
• For Use With (Application): Kinase Assay
• Formulation: 50 mM tris with 0.02% Triton X-100, 0.5 mM EDTA, 150 mM NaCl, 2 mM DTT, 50% glycerol and no preservative; pH 7.5
• Gene ID (Entrez): 120892
• Molecular Weight (g/mol): 288 kDa
• Name: LRRK2 [G2019S]
• Quantity: 100 μg
• Gene Alias: LRRK2
• Common Name: LRRK2 (G2019S Mutant)
• KinaseFamily: LRRK Kinase Family
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: DYKDDDDK-tag
• Sequence: Full length
• Content And Storage: -80°C, Avoid Freeze/Thaw Cycles
• Expression System: proprietary
• Form: Liquid