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Abcam LRRK2-IN-1, LRRK2 inhibitor, 10MG

Supplier:  Abcam AB25452410MG

Encompass_Preferred

MW 570.7 Da. Potent and selective inhibitor of the Parkinson's disease kinase LRRK2. Benzodiazepine based derivative. Inhibits both G2019S mutant and wild-type LRRK2 kinase activity (IC₅₀ values are 6 and 13 nM respectively). Causes dephosphorylation, ubiquitination and degradation of LRRK2. Inhibits IFN-γ-induced monocyte maturation in vitro.

The product is subject to the following: Abcam Restricted Use Statement

Catalog No. 50-267-2388


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