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Medchemexpress LLC Lupiwighteone | 104691-86-3 | 5 MG
SDP

Supplier:  Medchemexpress LLC HYN33545MG

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Lupiwighteone is an isoflavone from wild-growing plants with antioxidant, antimicrobial, and anticancer properties. It induces apoptosis in human breast cancer cells by inhibiting the PI3K/Akt/mTOR pathway. For research use only.

  • Antioxidant and antimicrobial effects.
  • Anticancer properties: induces apoptosis in breast cancer cells by inhibiting PI3K/Akt/mTOR.
  • Cytotoxicity against various cell lines (e.g., DU-145, SGC-7901).
  • Induces cell cycle arrest and apoptosis in DU-145 cells.
  • Dose-dependent reduction of cell cycle proteins (CDK1, 2, 4, 6, cyclinD1, B1) and increased ROS production.
  • Activates mitochondria-based intrinsic apoptosis, up-regulating cytochrome c and caspase-3, and down-regulating p-Akt/Akt and VEGF.

Catalog No. 50-004-17741


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