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Medchemexpress LLC Luteolin 7-O-glucuronide | 29741-10-4 | 462.36 | 1 ML
SDP

Supplier:  Medchemexpress LLC HYN146310MM/1ML

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Luteolin 7-O-glucuronide is an inhibitor of Matrix Metalloproteinases (MMP) activities, with IC50s of 17.63, 7.99, 11.42, 12.85, and 0.03 μM for MMP-1, MMP-3, MMP-8, MMP-9, and MMP-13, respectively. It is intended for research use only.

  • Inhibits NO production and mRNA expression of inflammatory mediators in LPS-stimulated RAW 264.7 macrophages.
  • Inhibits NF-κB, p38, and JNK activation in LPS-stimulated RAW 264.7 macrophages.
  • Improves depression-like and stress coping behaviors in mouse sleep deprivation models.
  • Reduces increased immobility time and plasma corticosterone levels.
  • Reduces TNF-α and IL-1β levels and increases BDNF mRNA expression in the hippocampus of sleep-deprived mice.

Catalog No. 50-004-15307


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