Sigma Aldrich Fine Chemicals Biosciences Luteolin 98 TLC powder50MG

Supplier:  Sigma Aldrich Fine Chemicals Biosciences L928350MG

Luteolin (3AE 4AE 5AE 7AE-tetrahydroxyflavone) a polyphenolic compound belongs to flavones subclass of flavonoids. Luteolin is commonly found in plants like celery green peppers and chamomile tea. Luteolin is one of the major flavonoids present in the flower extract of Hieracium pannosum Boiss aerial part of Dracocephalum kotschyi and contributes to the antioxidant potential of the plant. Luteolin possesses antioxidant anti-inflammatory properties and exerts anti-tumor potential primarily through apoptosis. Luteolin exerts its apoptotic activity through downregulation of protein kinase B (Akt) pathway leading to caspase mediated apoptosis. Luteolin also resensitizes cancer cells to therapeutics. Luteolin regulates the inflammatory genes and reduces nitric oxide and inflammatory cytokine production. The anti-inflammatory property of luteolin implicates it as a potential therapeutic agent for the neurodegenerative disease like Alzheimer disease. In plants luteolin induces nodu

Catalog No. 50-290-2272