Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Enzo Life Sciences LY 294002 (25 mg). CAS: 154447-36-6
Supplier: Enzo Life Sciences BMLST4200025
Potent, cell permeable, inhibitor of PI(3)K (phosphoinositide 3-kinase) that acts on the ATP-binding site of the enzyme. Displays an IC50 of 1.4µM and inhibits all isoforms equally in in vitro assays using purified PI 3-kinase (p110α IC50=0.63µM). Inhibits Pim-1 kinase with IC50=4.0µM. Other kinases such as PKC, PKA, MAP kinase, S6 kinase, EGF receptor tyrosine kinase, c-src kinase, PI 4-kinase, diacylglycerol kinase or rabbit kidney ATPase are not inhibited at 50µM. Induces apoptosis in many cell types by blocking the PI3-K/Akt anti-apoptotic pathway. Useful tool for identifying cellular events which are regulated by the PI3-K/Akt axis. Sensitizes tumor cells to drug-induced apoptosis independent of its PI3K inhibitory activity. I Alternative name: 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO (25mg/ml, warm), 100% ethanol (25mg/ml, warm) or methanol. Long Term Storage: -20°C.
Product Content Correction
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction