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AdipoGen LY-333 531 hydrochloride

Supplier: AdipoGen AGCR10087M001

Chemical. CAS 169939-93-9. Formula C28H28N4O3 . HCl. MW 468.6 . 36.5. Isozyme selective inhibitor of protein kinase Cbeta PKCbeta. PKCbetaI and PKCbetaII isozyme inhibitor. Amelioriates diabetic retinopathy, diabetic peripheral neuropathy and diabetic nephropathy. Anti-cancer and anti-angiogenic compound. Suppresses glucose-induced adhesion of human monocytes to endothelial cells. Suppresses ERK1/2 and Akt phosphorylation.
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