Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 502240389

Apexbio Technology LLC LY 379268,5mg CAS# 191471-52-0
SDP

Supplier:  Apexbio Technology LLC B70615

Encompass_Preferred

LY 379268 is a highly selective group II mGlu receptor agonist with EC50 value of 2.69 and 4.48 nM for hmGlu2 and hmGlu3, respectively [1].mGluRs is a type of glutamate receptor that is being considered as targets for the therapeutic intervention in neurodegenerative disorders. Activation of Group II mGluRs can protect cultured neurones against excitotoxic damage by inhibiting glutamate release [1].In the CA1 hippocampal cells, LY379268 reduced the ischemia-induced hyperactivity and provided protection after 5-min bilateral carotid artery occlusion (BCAO). Furthermore, before 5-min BCAO, 24- or 48-h pretreatment with LY379268 educed the damage to CA1 hippocampal neurons in a gerbil model [2]. Other sizes are also available. Please inqury us for quote.

Catalog No. 50-224-0389


May include imposed supplier surcharges.
Only null left
Add to Cart
This item is not returnable. View return policy

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.