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Selleck Chemical LLC LY2811376 5mg 1194044-20-6
Supplier: Selleck Chemical LLC S15285MG
LY2811376 is the first orally available non-peptidic ?-secretase(BACE1) inhibitor with IC50 of 239 nM-249 nM, that act to decrease A? secretion with EC50 of 300 nM, demonstrated to have 10-fold selectivity towards BACE1 over BACE2, and more than 50-fold inhibition over other aspartic proteases including cathepsin D, pepsin, or renin. Phase 1. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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