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Echelon Biosciences Research Labs LY294002 (HCI SALT) 5 mg
Supplier: Echelon Biosciences Research Labs B02945MG
LY294002 is a selective, cell permeable, potent and specific inhibitor of phosphatidylinositol 3-kinase (IC50 = 1.4 M; purified PI 3-kinase). It does not significantly inhibit PKC, PKA, MAP kinase, S6 kinase, EGFrK, c-src kinase, PI 4-kinase, DAG kinase or rabbit kidney ATPase at concentrations of 50 M. Induces apoptosis. In intact neutrophils stimulated with fMet-Leu-Phe, LY294002 completely abolished PI 3-kinase activity at 50 M without cell toxicity.nn
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Specifications
nProvided as HCl saltnNot SterilenFeatured in Publications
nDocuments
nTechnical Data Sheet This item is non returnable
This item is not returnable.
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