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Echelon Biosciences Research LabsSupplier Diversity Partner LY294002 (HCI SALT) 5 mg  DFS Item

Manufacturer:  Echelon Biosciences Research LabsSupplier Diversity Partner B02945MG

LY294002 is a selective, cell permeable, potent and specific inhibitor of phosphatidylinositol 3-kinase (IC50 = 1.4 μM; purified PI 3-kinase). It does not significantly inhibit PKC, PKA, MAP kinase, S6 kinase, EGFrK, c-src kinase, PI 4-kinase, DAG kinase or rabbit kidney ATPase at concentrations of 50 μM. Induces apoptosis. In intact neutrophils stimulated with fMet-Leu-Phe, LY294002 completely abolished PI 3-kinase activity at 50 μM without cell toxicity.\n\n

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Specifications

\nProvided as HCl salt\nNot Sterile\n

Featured in Publications

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Documents

\nTechnical Data Sheet

Catalog No. 50-720-011


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