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Echelon Biosciences Research Labs LY294002 (HCI SALT) 5 mg
SDP

Supplier:  Echelon Biosciences Research Labs B02945MG

Encompass

LY294002 is a selective, cell permeable, potent and specific inhibitor of phosphatidylinositol 3-kinase (IC50 = 1.4 M; purified PI 3-kinase). It does not significantly inhibit PKC, PKA, MAP kinase, S6 kinase, EGFrK, c-src kinase, PI 4-kinase, DAG kinase or rabbit kidney ATPase at concentrations of 50 M. Induces apoptosis. In intact neutrophils stimulated with fMet-Leu-Phe, LY294002 completely abolished PI 3-kinase activity at 50 M without cell toxicity.nn

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Specifications

nProvided as HCl saltnNot Sterilen

Featured in Publications

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Documents

nTechnical Data Sheet This item is non returnable

Catalog No. 50-720-011


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