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Cayman Chemical LY334370hydrochlorIde 10mg
Supplier: Cayman Chemical 2948110 MG
A 5-HT1F receptor agonist (Kd =0.446 nM); selective for 5-HT1F over other G protein-coupled 5-HT receptor subtypes (Kis = 16.4->3,000 nM); inhibits forskolin-induced cAMP accumulation in mouse L-M(TK-) cell membranes expressing the recombinant human 5-HT1F receptor (EC50 = 1.51 nM); decreases electrically stimulated extravasation of plasma proteins in the dura mater in a guinea pig trigeminal nerve model of migraine headache.
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