Cayman Chemical Lycors radta Ungeremn 10mg

Supplier:  Cayman Chemical 3454910 MG

A betaine-type alkaloid with diverse biological activities; an inhibitor of AChE (IC50 = 0.35 µM); a topoisomerase-IIβ poison; inhibits the relaxation of supercoiled DNA by human topoisomerase I and -IIα and E. coli topoisomerase I and -IV (IC50s = 6.1, 25.8, 15, and 7.3 µM, respectively); inhibits the growth of a variety of cancer cells (IC50s = 0.7-2.5 µM); cytotoxic to a variety of drug-sensitive and -resistant cancer cells (IC50s = 4.89-6.45 and 3.67-75.24 µM, respectively); induces ferroptosis, necroptosis, apoptosis, and autophagy in CCRF-CEM leukemia cells; reduces tumor growth in a GXF251L mouse xenograft model at 60 mg/kg twice per week

Catalog No. 50-295-0843