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Medchemexpress LLC Lyg-409 | 3053857-55-6 | 98.1% | 515.44 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY17095210MM/1ML

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LYG-409 is an orally active degrader of GSPT1. It demonstrates excellent anti-acute myeloid leukemia and prostate cancer activity in vivo, with TGI of 94.34% and 104.49%, respectively. It inhibits KG-1 cells by degrading GSPT1, with an IC50 of 9.50 nM and a DC50 of 7.87 nM in vitro.

  • Orally active degrader of GSPT1
  • Excellent anti-acute myeloid leukemia and prostate cancer activity in vivo
  • Inhibits KG-1 cells mediated by GSPT1 degradation

Catalog No. 50-003-86499


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