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Medchemexpress LLC Lys-CoA TFA (Lys-coenzyme A) | 98.5% | 1 MG
SDP

Supplier:  Medchemexpress LLC HY1310351MG

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Lys-CoA TFA is a selective p300 histone acetyltransferase (HAT) inhibitor with an IC50 of 50-500 nM. It demonstrates over 100-fold selectivity for p300 compared to PCAF (IC50=200 μM). This compound works by inhibiting p300 HAT activity-dependent transcriptional activation.

  • Selective p300 histone acetyltransferase (HAT) inhibitor
  • IC50 of 50-500 nM for p300
  • Over 100-fold selectivity for p300 compared to PCAF
  • Induces a senescent phenotype in human normal melanocytes at 0.1 and 1 mM concentrations
  • Inhibits cyclin E expression in a dose-dependent manner

Catalog No. 50-003-41008


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