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CPC Scientific H-Ala-Thr-Lys-Ala-Ala-Arg-Lys(Me3)-Ser-Ala-Pro-Ala-Thr-Gly-Gly-Val-Lys-Lys-Pro-His-Arg-Tyr-Arg-Pro-Gly-Lys(Biotin)-OH (trifluoroacetate salt) 1MG
Supplier: CPC Scientific HIST058B
This peptide is the fragment of Histone H3 (21-44) tri-methylated at Lys27 with an additional C-terminal Lys and biotinylation on the epsilon side chain of this Lys. Tri-methylation of Lys27 promotes Polycomb protein (Pc)-chromatin association and is associated with heterochromatin assembly and gene silencing.ONE-LETTER SEQUENCE: ATKAAR-K(Me3)-SAPATGGVKKPHRYRPG-K(Biotin)MOLECULAR FORMULA: MOLECULAR WEIGHT:2902.4STORAGE CONDITIONS: -20 5CRESEARCH AREA: MiscellaneousREFERENCES: Zhang, X. et al. Nat Struct Mol Biol 14, 869 (2007); Min, J. et al. Genes Dev 17, 1823 (2003)
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