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Cayman Chemical Lyso-Monosialoganglioside GM2
Supplier: Cayman Chemical 33073500 UG
A ganglioside lacking the fatty acyl group; inhibits PKC in a cell-free assay (IC50 = 50 µM); gray matter levels are increased in postmortem brain samples from patients with Sandhoff disease or Tay-Sachs disease, as well as a mouse model of Sandhoff disease
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