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Dojindo Molecular Technologies Inc LysoPrime Green (10 μL x 3). High selectivity for lysosomes, high retention even in lysosomes that had their pH neutralized after staining, long-term visualization of lysosomes, Ex=456 nm, Ex=540 nm.
Supplier: Dojindo Molecular Technologies Inc L26112
Understanding lysosome-related physiology requires lysosome-specific probes that can track the behavior of lysosomes within cells. As a consequence of being designed simply to target acidic environments, most lysosomal probes have poor specificity towards the lysosome and stain many non-lysosomal acidic compartments. Moreover, existing lysosome probes’ fluorescent intensity is highly reliant on the lysosomes’ pH; their emission intensity is unstable and varies significantly due to differences in acidity among lysosomes, even within a cell. (https://dojindo.com/lms-mapselectionguide/)
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