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Medchemexpress LLC m-PEG-NHS ester | 92451-01-9 | 98.0% | Poly(oxy-1,2-ethanediyl), α-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-ω-methoxy- | 250 MG

Supplier: Medchemexpress LLC 250MGHY140699
m-PEG-NHS ester (MW 10000) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs consist of two distinct ligands connected by a linker, where one ligand targets an E3 ubiquitin ligase and the other targets a specific protein, thereby leveraging the intracellular ubiquitin-proteasome system to facilitate the selective degradation of target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Targets PROTAC linkers
- Exploits the intracellular ubiquitin-proteasome system
- Facilitates selective degradation of target proteins
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