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Medchemexpress LLC m-PEG-NHS ester (MW 10000) | 92451-01-9 | 98.0% | Poly(oxy-1,2-ethanediyl), α-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-ω-methoxy- | 1 G
SDP

Supplier:  Medchemexpress LLC HY1406991G

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m-PEG-NHS ester (MW 10000) is a PEG-based PROTAC linker designed for the synthesis of PROTACs. These molecules feature two distinct ligands joined by a linker: one targeting an E3 ubiquitin ligase and the other binding to a specific target protein. This mechanism allows PROTACs to leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.

  • PEG-based PROTAC linker
  • Used in the synthesis of PROTACs
  • Exploits the ubiquitin-proteasome system to degrade target proteins
  • Solid, white to off-white appearance
  • For research use only

Catalog No. 50-003-56631


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