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Medchemexpress LLC M-PEG-NHS ester (MW 10000) | 92451-01-9 | 98.0% | Poly(oxy-1,2-ethanediyl), α-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-ω-methoxy- | 25 MG

Supplier: Medchemexpress LLC 25MGHY140699
m-PEG-NHS ester (MW 10000) is a PEG-based PROTAC linker. It is for research use only and not sold to patients. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. These compounds contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Composed of PEG, alkyl, and ether groups
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