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Medchemexpress LLC M-PEG-thiol (MW 2000) | 134874-49-0 | 99.8% | COCCOCCS.[MW 2000].[n] | 50 MG
Supplier: Medchemexpress LLC HY14070650MG
M-PEG-thiol (MW 2000) is a PEG-based PROTAC linker used in the synthesis of PROTACs. These molecules feature two distinct ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other for the target protein. PROTACs harness the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Contains two different ligands connected by a linker
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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