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Medchemexpress LLC m-PEG-thiol (MW 20000) | 95.0% | 100 MG
Supplier: Medchemexpress LLC HY140709100MG
m-PEG-thiol (MW 20000) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are compounds designed with two ligands connected by a linker, one targeting an E3 ubiquitin ligase and the other a target protein. This mechanism exploits the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins.
- Functions as a PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs contain two different ligands connected by a linker
- One ligand targets an E3 ubiquitin ligase
- Other ligand targets a specific protein
- Exploits the intracellular ubiquitin-proteasome system
- Designed for selective degradation of target proteins
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