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Medchemexpress LLC m-PEG12-azide | 2170098-29-8 | 98.6% | C25H51N3O12 | 250 MG
Supplier: Medchemexpress LLC 250MGHY140830
m-PEG12-azide is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent with an Azide group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions. This linker helps PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins. It appears as a colorless to light yellow liquid and is intended for research use only.
- PEG-based linker for PROTAC synthesis
- Click chemistry reagent with azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC)
- Leverages ubiquitin-proteasome system for target protein degradation
- Colorless to light yellow liquid appearance
- Intended for research use only
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