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Medchemexpress LLC M-PEG12-Br | 1620461-89-3 | C25H51BrO12 | 250 MG

Supplier: Medchemexpress LLC 250MGHY141378
m-PEG12-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is for research use only and not sold to patients. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Key component in the creation of PROTACs.
- Functions by connecting a ligand for an E3 ubiquitin ligase with a ligand for a target protein.
- Harnesses the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
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