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Medchemexpress LLC M-PEG12-NHS ester | 2207596-93-6 | >=98.0% | C30H55NO16 | 100 MG
Supplier: Medchemexpress LLC HY141106100MG
m-PEG12-NHS ester is a PEG-based PROTAC linker that plays a crucial role in the synthesis of PROTACs. These molecules are designed with two distinct ligands, one targeting an E3 ubiquitin ligase and the other a target protein. This innovative mechanism enables PROTACs to leverage the intracellular ubiquitin-proteasome system for the selective degradation of specific target proteins, offering a novel approach in drug discovery.
- Utilized in the synthesis of PROTACs
- Features a PEG-based linker
- Facilitates targeted protein degradation
- Leverages the ubiquitin-proteasome system
- Designed for research use
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