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Medchemexpress LLC M-PEG4-NH-DBCO | 2228857-36-9 | 95.0% | C28H34N2O6 | 25MG

Supplier: Medchemexpress LLC 25MGHY140315
m-PEG4-NH-DBCO is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. It functions as a click chemistry reagent, containing a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. PROTACs are compounds that leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins, typically comprising two different ligands connected by a linker: one for an E3 ubiquitin ligase and the other for the target protein.
- PEG-based linker for PROTAC synthesis
- Functions as a click chemistry reagent
- Contains a DBCO group
- Facilitates strain-promoted alkyne-azide cycloaddition (SPAAC)
- Enables SPAAC with azide-containing molecules
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