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Medchemexpress LLC M-PEG4-NH-DBCO | 2228857-36-9 | 95.0% | C28H34N2O6 | 25MG
SDP

Supplier:  Medchemexpress LLC 25MGHY140315

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m-PEG4-NH-DBCO is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. It functions as a click chemistry reagent, containing a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. PROTACs are compounds that leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins, typically comprising two different ligands connected by a linker: one for an E3 ubiquitin ligase and the other for the target protein.

  • PEG-based linker for PROTAC synthesis
  • Functions as a click chemistry reagent
  • Contains a DBCO group
  • Facilitates strain-promoted alkyne-azide cycloaddition (SPAAC)
  • Enables SPAAC with azide-containing molecules

Catalog No. 50-003-52675


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