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Medchemexpress LLC m-PEG7-CH2CH2COOH | 1093647-41-6 | 10 G
Supplier: Medchemexpress LLC HY13015110G
m-PEG7-CH2CH2COOH is a non-cleavable ADC linker utilized in the creation of antibody-drug conjugates (ADCs). It also serves as a PEG-based PROTAC linker for the synthesis of PROTACs. ADCs consist of an antibody linked to an ADC cytotoxin via an ADC linker. PROTACs feature two distinct ligands connected by a linker: one targets an E3 ubiquitin ligase, and the other binds to the target protein. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Non-cleavable linker for antibody-drug conjugates
- PEG-based linker for PROTACs
- Exploits the ubiquitin-proteasome system
- Designed for selective degradation of target proteins
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