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CPC Scientific H-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Pro-Pro-Ala-Leu-Ala-Leu-Ala-NH2 (trifluoroacetate salt) 0.5MG

Supplier: CPC Scientific GALA005A
Antagonist of galanin receptor that significantly antagonizes galanin-induced feeding behavior at doses approximately equimolar to the active doses of rat galanin. It inhibits the binding of (125I-Tyr26)-galanin (porcine) in rat hypothalamic membranes with IC50 value of 15nM. ONE-LETTER SEQUENCE: GWTLNSAGYLLGPPPALALA-NH2MOLECULAR FORMULA: C94H145N23O24MOLECULAR WEIGHT:1981.33STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [143896-17-7], SYNONYMS: Galanin (1-13)-Pro-Pro-(Ala-Leu-)Ala amide RESEARCH AREA: Alzheimer's DiseaseREFERENCES: S.F. Leibowitz et al., Brain Res., 599, 148 (1992); J.N. Crawley et al., Brain Res., 600, 268 (1993); X. J. Xu et al., Br. J. Pharmacol., 116, 2076 (1995)
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