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Apexbio Technology LLC N6-methyladenosine (m6A) 1867-73-8 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B59935.1
N6-methyladenosine (m6A) is a purine derivative functioning primarily as an adenosine receptor agonist and modulates adenylate cyclase activity with reported ED50 approximately 17 25 M It is a common internal modification in eukaryotic messenger RNAs predominantly occurring within consensus motif RRACH (R G or A H A C or U) and affecting RNA stability processing and translation Experimental studies indicate m6A application in cellular models such as murine erythroleukemia (MEL) cells reduces -globin mRNA accumulation thereby suppressing erythroid differentiation initiation Due to its epigenetic regulatory role m6A serves as a tool for studying RNA methylation-dependent gene expression and cellular differentiation
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