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Apexbio Technology LLC m7GTP(Sodium salt) 104809-18-9 50ul (100 mM)

Supplier: Apexbio Technology LLC B88010.05
m7GTP (Sodium salt) chemically known as 7-methylguanosine 5 -triphosphate structurally resembles the 5 -cap of eukaryotic messenger RNA (mRNA) Due to its affinity for the eukaryotic initiation factor 4E (eIF4E) this compound frequently functions as an affinity ligand for isolating and studying translation initiation complexes Mechanistically m7GTP binds specifically to eIF4E thereby competitively inhibiting interaction with native capped mRNA and disrupting subsequent initiation complex formation during in vitro protein synthesis Consequently it serves as an essential research tool for examining translation initiation processes delineating mRNA cap recognition pathways and characterizing regulatory mechanisms governing eukaryotic protein synthesis
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