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Bio X Cell Antibody, Anti-Human/Mouse Ganglioside GD2, Clone 14G2a, Mouse IgG2a
Supplier: Bio X Cell BE0318R005MG
The 14G2a monoclonal antibody targets human ganglioside GD2, a glycolipid involved in cell attachment. GD2 is expressed on neuroectodermal tumors, such as neuroblastoma and melanoma, making it a target for immunotherapy. This clone is an isotype switch variant with identical reactivity to its parental antibody.
- Clone: 14G2a
- Reactivates with mouse and human cells
- Isotype: Mouse IgG2a, κ
- Supports in vitro induction of apoptosis in GD2+ cells
- Supports in vivo inhibition of GD2+ tumor cell growth
- Formulated in PBS, pH 7.0, without stabilizers or preservatives
- Endotoxin level: ≤1 EU/mg (≤0.001 EU/µg)
- Purity: ≥95%
- Sterility: 0.2 µm filtration
- Produced from cell culture supernatant in an animal-free facility
- Purified via Protein G
- Molecular weight: 150 kDa
- Store at stock concentration at 4°C, do not freeze
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