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Bio X Cell InVivoMAb, NKG2A/C/E, 20D5, Rat IgG2a, 50 MG
Supplier: Bio X Cell BE0321R050MG
The 20D5 monoclonal antibody reacts with mouse NKG2A, NKG2C, and NKG2E (CD159a, CD159c, and CD159e). These NKG2 receptors are C-type lectin-like receptors that form heterodimers with CD94 and are primarily expressed on NK cells and NKT cells. Blocking NKG2A signaling has been shown to promote anti-tumor immunity in murine tumor models, making NKG2A a target for novel immune checkpoint inhibitory therapy.
- Host species: Rat IgG2a, κ
- Target species: Mouse NKG2A, NKG2C, and NKG2E
- Applications: In vivo NKG2A blockade, in vitro NKG2A blockade, IHC (frozen), flow cytometry
- Formulation: PBS, pH 7.0 (no stabilizers/preservatives)
- Endotoxin: ≤1EU/mg
- Purity: ≥95% (SDS-PAGE)
- Sterility: 0.2 μm filtered
- Purification: Protein G
- Molecular weight: 150 kDa
- Storage: 4°C, do not freeze
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