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Bio X Cell Monoclonal Antibody, Human PD-L1 29E.2A3, 1 MG
Supplier: Bio X Cell BE0285R001MG
The 29E.2A3 monoclonal antibody reacts with human PD-L1 (programmed death ligand 1), also known as B7-H1 or CD274. PD-L1 is a 40 kDa type I transmembrane protein belonging to the B7 family of the Ig superfamily. It binds to its receptor, PD-1, leading to inhibition of TCR-mediated T cell proliferation and cytokine production. This antibody blocks the binding of PD-1-Ig to PD-L1.
- In vitro PD-L1 blockade
- Functional assays
- Immunohistochemistry (frozen)
- Flow cytometry
- In vitro organoids/organ-on-chip
- Isotype: mouse IgG2b, κ
- Purity: ≥95%, determined by SDS-PAGE
- Endotoxin: ≤1EU/mg (≤0.001EU/μg)
- Formulation: PBS, pH 7.0 (contains no stabilizers or preservatives)
- Storage: store at stock concentration at 4°C, do not freeze
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